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This webinar introduces the latest update to eProtein Discovery™, allowing researchers to customize cell-free expression conditions to improve yields of co-factor dependent membrane proteins.

Screen, Scale, Capture, Characterize – DNA to Protein Characterization in One Week Understanding drug–target interactions is essential to improve leads, optimize pharmacokinetics and predict in vivo efficacy. The process of generating soluble, functional drug targets and studying their interactions with drugs can be complicated and time-consuming, with multiple repeats needed to optimize protein expression and…

In this webinar, we will explore how the eProtein Discovery™ System addresses the challenges of expressing difficult-to-express proteins, such as transcription factors, proteins with disordered regions and disulfide bonds. Leveraging advanced cell-free protein synthesis (CFPS) and digital microfluidic technology, this system enables researchers to rapidly produce soluble, purified proteins within 48 hours.

The integration of AlphaFold AI within the eProtein Discovery™ framework brings forth a multitude of advantages, facilitating structure guided protein construct design with unprecedented precision.

The eProtein Discovery™ System can screen multiple protein expression and purification profiles and deliver reliable proteins in-hand in less than 48 hours. Revolutionizing laboratory workflows and making a demonstrable impact in terms of time to publish in academia and drug discovery timelines.

Overcoming the Inexpressible: How cell-free protein synthesis solved the E. coli toxicity hurdle. Learn how the eProtein Discovery™ enabled optimization of the expression conditions for an GCN5-Related N-Acetyltransferase protein and gain insights into its antibiotic resistance mechanism.